20(S)-Hydroxycholesterol( —— )

Catalog No. M32745 CAS No. 516-72-3

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

20(S)-Hydroxycholesterol
Note

Research use only, not for human use.
Brief Description

20(S)-Hydroxycholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo).
Description

20(S)-Hydroxycholesterol (Standard) is the analytical standard of 20(S)-Hydroxycholesterol. This product is intended for research and analytical applications. 20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells.
In Vitro

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In Vivo

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Synonyms

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Pathway

Wnt/Notch/Hedgehog
Target

Smoothened (Smo)
Recptor

Smo
Research Area

——
Indication

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CAS Number

516-72-3
Formula Weight

402.65
Molecular Formula

C27H46O2
Purity

>98% (HPLC)
Solubility

——
SMILES

C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@](CCCC(C)C)(C)O)[H])[H]
Chemical Name

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