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Cefepime
CAS No. 88040-23-7
Cefepime( —— )
Catalog No. M32734 CAS No. 88040-23-7
Cefepime (BMY-28142) is a cephalosporin antibiotic with antimicrobial activity, induces neurotoxicity, inhibits both Gram-positive and Gram-negative, and can be used in the study of anaerobic bacteria.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 41 | In Stock |
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| 25MG | 30 | In Stock |
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| 50MG | 37 | In Stock |
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| 100MG | 55 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCefepime
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NoteResearch use only, not for human use.
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Brief DescriptionCefepime (BMY-28142) is a cephalosporin antibiotic with antimicrobial activity, induces neurotoxicity, inhibits both Gram-positive and Gram-negative, and can be used in the study of anaerobic bacteria.
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DescriptionCefepime (BMY-28142) is a broad-spectrum and cross the blood-brain barrier cephalosporin. Cefepime shows antibacterial effects against both Gram-positive and Gram-negative aerobic bacteria. Cefepime induces neurotoxicity.
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In VitroCefepime chloride exerts its antibacterial effects by binding to penicillin-binding proteins.
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In VivoCefepime (80 mg/kg; i.p.) significantly increases the half-life and mice surviveed.Animal Model:Male CD-1 miceDosage:80 mg/kg Administration:I.p.Result:Significantly prolonged the half-life of cefepime and all mice survived at 18-22 mg/kg cisplatin, and when pretreatment with 26 mg/kg cisplatin significantly decreased survival with the half-life of cefepime was not significantly longer than of 18 mg/kg cisplatin.
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Synonyms——
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PathwayMicrobiology/Virology
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TargetAntibiotic
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RecptorAntibiotic | Antibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number88040-23-7
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Formula Weight480.56
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Molecular FormulaC19H24N6O5S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (260.11 mM; Ultrasonic ) H2O : 100 mg/mL (208.09 mM; Ultrasonic)
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SMILESC([O-])(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CSC(N)=N3)=O)C2=O)(SCC1C[N+]4(C)CCCC4)[H]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Yahav D, et al. Efficacy and safety of cefepime: a systematic review and meta-analysis. Lancet Infect Dis. 2007 May;7(5):338-48. ?
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