Cefepime( —— )

Catalog No. M32734 CAS No. 88040-23-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

Cefepime
Note

Research use only, not for human use.
Brief Description

Cefepime (BMY-28142) is a cephalosporin antibiotic with antimicrobial activity, induces neurotoxicity, inhibits both Gram-positive and Gram-negative, and can be used in the study of anaerobic bacteria.
Description

Cefepime (BMY-28142) is a broad-spectrum and cross the blood-brain barrier cephalosporin. Cefepime shows antibacterial effects against both Gram-positive and Gram-negative aerobic bacteria. Cefepime induces neurotoxicity.
In Vitro

Cefepime chloride exerts its antibacterial effects by binding to penicillin-binding proteins.
In Vivo

Cefepime (80 mg/kg; i.p.) significantly increases the half-life and mice surviveed.Animal Model:Male CD-1 miceDosage:80 mg/kg Administration:I.p.Result:Significantly prolonged the half-life of cefepime and all mice survived at 18-22 mg/kg cisplatin, and when pretreatment with 26 mg/kg cisplatin significantly decreased survival with the half-life of cefepime was not significantly longer than of 18 mg/kg cisplatin.
Synonyms

——
Pathway

Microbiology/Virology
Target

Antibiotic
Recptor

Antibiotic | Antibacterial
Research Area

——
Indication

——

CAS Number

88040-23-7
Formula Weight

480.56
Molecular Formula

C19H24N6O5S2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (260.11 mM; Ultrasonic ) H2O : 100 mg/mL (208.09 mM; Ultrasonic)
SMILES

C([O-])(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CSC(N)=N3)=O)C2=O)(SCC1C[N+]4(C)CCCC4)[H]
Chemical Name

——

1. Yahav D, et al. Efficacy and safety of cefepime: a systematic review and meta-analysis. Lancet Infect Dis. 2007 May;7(5):338-48. ?

Calculator

molnova catalog