Cefepime

Research use only, not for human use.

Cefepime (BMY-28142) is a cephalosporin antibiotic with antimicrobial activity, induces neurotoxicity, inhibits both Gram-positive and Gram-negative, and can be used in the study of anaerobic bacteria.

Cefepime (BMY-28142) is a broad-spectrum and cross the blood-brain barrier cephalosporin. Cefepime shows antibacterial effects against both Gram-positive and Gram-negative aerobic bacteria. Cefepime induces neurotoxicity.

Cefepime chloride exerts its antibacterial effects by binding to penicillin-binding proteins.

Cefepime (80 mg/kg; i.p.) significantly increases the half-life and mice surviveed.Animal Model:Male CD-1 miceDosage:80 mg/kg Administration:I.p.Result:Significantly prolonged the half-life of cefepime and all mice survived at 18-22 mg/kg cisplatin, and when pretreatment with 26 mg/kg cisplatin significantly decreased survival with the half-life of cefepime was not significantly longer than of 18 mg/kg cisplatin.

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Microbiology/Virology

Antibiotic

Antibiotic | Antibacterial

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88040-23-7

480.56

C19H24N6O5S2

>98% (HPLC)

In Vitro:?DMSO : 125 mg/mL (260.11 mM; Ultrasonic ) H2O : 100 mg/mL (208.09 mM; Ultrasonic)

C([O-])(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CSC(N)=N3)=O)C2=O)(SCC1C[N+]4(C)CCCC4)[H]

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(-20℃)

With Ice Pack

≥ 2 years