Tumulosic acid
CAS No. 508-24-7
Tumulosic acid( —— )
Catalog No. M32345 CAS No. 508-24-7
Tumulosic acid is a natural product for research related to life sciences.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 322 | In Stock |
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| 50MG | Get Quote | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameTumulosic acid
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NoteResearch use only, not for human use.
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Brief DescriptionTumulosic acid is a natural product for research related to life sciences.
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DescriptionTumulosic acid is a natural product for research related to life sciences.
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In VitroTumulosic acid displays dose-dependent anti-KLK5 activity (IC50=19.3 μM).Tumulosic acid decreases in LL-37 production in human keratinocytes. Tumulosic acidshows IC50 values of 14.84 and 10.48 μM against KLK5 and trypsin proteases, while it exhibited a weak inhibitory effect on KLK7 and chymotrypsin C proteases (19.5% and 4.0%, respectively, at 100 μM). Western Blot Analysis Cell Line:Normal human epidermal keratinocytes (NHEKs) Concentration:1 μM and 10 μM Incubation Time:23 h in the presence of 10 μM cycloheximide Result:Decreased LL-37 production in epidermal keratinocytes.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number508-24-7
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Formula Weight486.7
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Molecular FormulaC31H50O4
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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24-Norursodeoxycholi...
24-norursodeoxycholic acid is a side chain-shortened C23 homolog of UDCA.It has shown potent anti-inflammatory, anti-cholestatic, and anti-fibrotic properties.It is a Ursodeoxycholic Acid derivative. It is superior to Ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice24-norUrsodeoxycholic acid markedly improved liver tests and liver histology and significantly reduced hydroxyproline content and the number of infiltrating neutrophils and proliferating hepatocytes and cholangiocytes.?
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Humantenine
Humantenine is a indole alkaloid compound isolated from Gelsemium elegans.
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Polygalasaponin V
Polygalasaponin possesses evident anxiolytic and sedative-hypnotic activities and has a relatively safe dose range, which supports the use of Polygala tenuifolia root as an anxiolytic and sedative-hypnotic drug in folk medicine.
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