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Taurocholic acid
CAS No. 81-24-3
Taurocholic acid( —— )
Catalog No. M31531 CAS No. 81-24-3
Taurocholic acid is a bile acid involved in the emulsification of fats.Taurocholic acid is cytoprotective, preventing tumor necrosis factor-alpha-induced cholangiocyte damage via a PI3K-mediated pathway.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 50 | In Stock |
|
| 10MG | 73 | In Stock |
|
| 50MG | Get Quote | In Stock |
|
| 100MG | Get Quote | In Stock |
|
Biological Information
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Product NameTaurocholic acid
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NoteResearch use only, not for human use.
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Brief DescriptionTaurocholic acid is a bile acid involved in the emulsification of fats.Taurocholic acid is cytoprotective, preventing tumor necrosis factor-alpha-induced cholangiocyte damage via a PI3K-mediated pathway.
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DescriptionTaurocholic acid is a bile acid involved in the emulsification of fats.Taurocholic acid is cytoprotective, preventing tumor necrosis factor-alpha-induced cholangiocyte damage via a PI3K-mediated pathway.
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In VitroTaurocholic acid (100 μM, 24 h) decreases the proportion of CD3+CD8+ T and NK cells in isolated PBMCs from HBeAg-positive CHB patients.Taurocholic acid (100 μM, 24 h) decreases IFN-α stimulated cytokine and cytotoxic granule levels (IFN-γ, TNF-α, granzyme B) in CD3+CD8+ T and NK cells.
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In VivoAnimal Model:C57BL/6 mice Dosage:100-mg/kg Administration:oral gavage, for 2 weeks after tail vein injection with rAAV8-1.3HBV for 6 weeks Result:Reduced the percentage of NK and CD3+CD8+ T cells.Increases serum HBsAg, HBeAg, and HBV DNA levels.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number81-24-3
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Formula Weight515.7
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Molecular FormulaC26H45NO7S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (193.91 mM)
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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4-Hydroxybenzoic aci...
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