25S-Inokosterone

CAS No. 19595-18-7

25S-Inokosterone( —— )

Catalog No. M31435 CAS No. 19595-18-7

25S-Inokosterone and 25R-inokosterone exhibit potent inhibition (80-95% at ) against TNF-expression levels in A23187 plus phorbol-myrisrate acetate-induced RBL-2H3 cells, they have excellent anti-atopy activity, thus they could be used to a large range of functional anti-atopy cosmetics.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    25S-Inokosterone
  • Note
    Research use only, not for human use.
  • Brief Description
    25S-Inokosterone and 25R-inokosterone exhibit potent inhibition (80-95% at ) against TNF-expression levels in A23187 plus phorbol-myrisrate acetate-induced RBL-2H3 cells, they have excellent anti-atopy activity, thus they could be used to a large range of functional anti-atopy cosmetics.
  • Description
    25S-Inokosterone and 25R-inokosterone exhibit potent inhibition (80-95% at ) against TNF-expression levels in A23187 plus phorbol-myrisrate acetate-induced RBL-2H3 cells, they have excellent anti-atopy activity, thus they could be used to a large range of functional anti-atopy cosmetics.
  • In Vitro
    25S-Inokosterone (10 μM) significantly promotes the proliferation of LPS-induced NRK52e cells (1.0 μg/mL LPS). 25S-Inokosterone significantly reduces the rate of NRK52e cells apoptosis. 25S-Inokosterone shows weak inhibitory activity for thymus and activation-regulated chemokine expression levels in TNF-α plus IFN-γ induced HaCaT cells. 25S-Inokosterone exhibits the most potent inhibition (80-95% at 200 μg/mL) against TNF-α expression levels in A23187 plus phorbol-myrisrate acetate-induced RBL-2H3 cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    19595-18-7
  • Formula Weight
    480.6
  • Molecular Formula
    C27H44O7
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

molnova catalog
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