Itaconate-alkyne is a bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of itaconate in inflammatory macrophages and enables biochemical evaluation and proteomic analysis of its direct targets.

Wogonin is a naturally occurring mono-flavonoid, can inhibit the activity of CDK8 and Wnt, and exhibits anti-inflammatory and anti-tumor effects.

Isorhoifolin and vicenin II are main compounds of ethyl acetate fraction (EAcF) obtained from Erythrina velutina leaves, EAcF increases the cardiac contractile force by increasing the l-type calcium current and activating the adrenergic receptor pathway.