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Kuraridine
CAS No. 34981-25-4
Kuraridine( —— )
Catalog No. M31175 CAS No. 34981-25-4
Kuraridine is measured against cGMP PDE5 to identify potent cGMP specific phosphodiesterase type 5 inhibitory constituents.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameKuraridine
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NoteResearch use only, not for human use.
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Brief DescriptionKuraridine is measured against cGMP PDE5 to identify potent cGMP specific phosphodiesterase type 5 inhibitory constituents.
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DescriptionKuraridine is measured against cGMP PDE5 to identify potent cGMP specific phosphodiesterase type 5 inhibitory constituents.
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In VitroKuraridine shows potent inhibitory activity (IC50=0.64 μM) against cGMP PDE5 with 2.0- and 12.9-fold selectivity over PDE3 and PDE4, respectively.Kuraridine induces pronounced chloride inward currents in the absence of GABA. Thecurrents does not exceed 10% of the maximal?IGABA?induced by a saturating GABA concentration (1 mM).Kuraridine induces a concentration–response curves for?IGABA?enhancement (EC50=4.0±2.4 μM) in Xenopus?oocytes expressing GABAA?receptors composed of?α1, β2, and?γ2S?subunits.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number34981-25-4
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Formula Weight438.5
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Molecular FormulaC26H30O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 100 mg/mL (228.04 mM)
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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