6-Hydroxyrubiadin( —— )

Catalog No. M31087 CAS No. 87686-86-0

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Product Name

6-Hydroxyrubiadin
Note

Research use only, not for human use.
Brief Description

6-Hydroxyrubiadin has antioxidant activity, EC(50) is 14.7ug/ml.
Description

6-Hydroxyrubiadin has antioxidant activity, EC(50) is 14.7ug/ml.
In Vitro

6-hydroxyrubiadin suppresses lipopolysaccharide (LPS)-induced nuclear factor-kappa B activation as well as the phosphorylation of c-Jun N-terminal kinase in RAW 264.7 macrophages.6-hydroxyrubiadin inhibited the expression of tumor necrosis factor (TNF)-a, interleukin (IL)-1b and IL-6 in phorbol myristate acetate (PMA)-primed U937 and RAW 264.7cells.
In Vivo

6-hydroxyrubiadin can reduce the production of pro-inflammatory cytokines and ameliorate acute lung injury (ALI) in a mouse model.
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