Jacobine
CAS No. 6870-67-3
Jacobine( —— )
Catalog No. M31064 CAS No. 6870-67-3
Jacobine induces significant dose-dependent DNA-DNA interstrand cross-linking over the entire range of doses.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameJacobine
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NoteResearch use only, not for human use.
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Brief DescriptionJacobine induces significant dose-dependent DNA-DNA interstrand cross-linking over the entire range of doses.
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DescriptionJacobine induces significant dose-dependent DNA-DNA interstrand cross-linking over the entire range of doses. It was catalyzed by guinea pig hepatic glutathione-S-transferase enzymes in in vitro experiments.
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In VitroPyrrolizidine?alkaloids?(PAs) at plant concentration reduce thrips survival on average with 21%. Structurally related PAs affect survival of thrips differently. PA free bases reduce thrips survival more than the corresponding PA?N-oxides.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number6870-67-3
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Formula Weight351.4
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Molecular FormulaC18H25NO6
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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MTOB
MTOB is a substrate for c-terminal binding protein (CtBP) that interferes with the carcinogenic activity of CtBP in cell culture and mice. It also actively regulates TCF-4 signaling, leading to cancer stem cell (CSC) growth and self-renewal.
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Hepcidin-1 (mouse) t...
Hepcidin-1 (mouse) is an endogenous peptide hormone involved in the regulation of iron homeostasis. Hepcidin-1 (mouse) upregulates mRNA levels of TRAP, cathepsin K, and MMP-9 and increases TRAP-5b protein secretion. Hepcidin-1 (mouse) downregulates the level of FPN1 protein and increases intracellular iron. Hepcidin-1 (mouse) facilitates osteoclast differentiation.
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L-Methionine-DL-sulf...
L-Methionine-DL-sulfoximine inhibits glutamine synthetase and metabolically and morphologically primarily affects astroglia. L-Methionine-DL-sulfoximine can be used in convulsant studies.
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