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Somatostatin-28 1-14
CAS No. 79243-10-0
Somatostatin-28 1-14( —— )
Catalog No. M30521 CAS No. 79243-10-0
Somatostatin-28 (1-14) is an N-terminal fragment of the neuropeptide somatostatin-28. Somatostatin 28 arises from the posttranslational cleavage of prosomatostatin, which in turn is derived from a large precursor, preprosomatostatin.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 10MG | 826 | Get Quote |
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Biological Information
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Product NameSomatostatin-28 1-14
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NoteResearch use only, not for human use.
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Brief DescriptionSomatostatin-28 (1-14) is an N-terminal fragment of the neuropeptide somatostatin-28. Somatostatin 28 arises from the posttranslational cleavage of prosomatostatin, which in turn is derived from a large precursor, preprosomatostatin.
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DescriptionSomatostatin-28 (1-14) is an N-terminal fragment of the neuropeptide somatostatin-28. Somatostatin 28 arises from the posttranslational cleavage of prosomatostatin, which in turn is derived from a large precursor, preprosomatostatin.(In Vitro):The tetradecapeptide hormone somatostatin arises from proteolytic processing of a large precursor, preprosomatostatin. Somatostatin-28 (1-14) has been used to produce antibodies selective for somatostatin-28 that do not bind to the C-terminal fragment somatostatin-14.
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In VitroThe tetradecapeptide hormone somatostatin arises from proteolytic processing of a large precursor, preprosomatostatin. Somatostatin-28 (1-14) has been used to produce antibodies selective for somatostatin-28 that do not bind to the C-terminal fragment somatostatin-14.
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetSomatostatin Receptor
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number79243-10-0
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Formula Weight1528.71
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Molecular FormulaC61H105N23O21S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (65.41 mM)
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SMILES——
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Chemical NameSequence:Ser-Ala-Asn-Ser-Asn-Pro-Ala-Met-Ala-Pro-Arg-Glu-Arg-Lys
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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CH 275
Potent somatostatin receptor 1 (sst1) agonist; displays selectivity for sst1 (IC50 values are 30.9 nM, 345 nM, > 1 μM, > 10 μM and > 10μM for human sst1, sst3, sst4, sst2 and sst5 respectively). Attenuates somatostatin release in the rat nucleus accumbens.
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CYN 154806 TFA(18365...
CYN 154806 (TFA) is a cyclic octapeptide and an effective selective somatostatin sst2 receptor antagonist. For the recombinant sst2, sst1, sst3, sst4 and sst5 receptors, the pIC50 values are 8.58, 5.41, 6.07, 5.76 and 6.48, respectively.
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Cortistatin-14
Cortistatin 14 is a neuropeptide expressed in inhibitory neurons of the cerebral cortex. Depresses neuronal activity, and induces slow-wave sleep, likely through antagonism of acetylcholine. It is structurally and functionally similar to somatostatin 14. Competes with somatostatin 14 for binding of somatostatin receptors (IC50s=5, 0.09, 0.3, 0.2, and 0.3nM for receptors sst1-5, respectively).
