[Sar1, Ile8]-Angiotensin II
CAS No. 37827-06-8
[Sar1, Ile8]-Angiotensin II( —— )
Catalog No. M30451 CAS No. 37827-06-8
[Sar1, Ile8]-Angiotensin II is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels. The biological activities of angiotensin II antagonists upon basal and angiotensin II-stimulated aldosterone production were evaluated in an isolated canine glomerulosa cell preparation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
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| 5MG | 63 | Get Quote |
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| 10MG | 88 | Get Quote |
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| 25MG | 160 | Get Quote |
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| 50MG | 240 | Get Quote |
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| 100MG | 361 | Get Quote |
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Biological Information
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Product Name[Sar1, Ile8]-Angiotensin II
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NoteResearch use only, not for human use.
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Brief Description[Sar1, Ile8]-Angiotensin II is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels. The biological activities of angiotensin II antagonists upon basal and angiotensin II-stimulated aldosterone production were evaluated in an isolated canine glomerulosa cell preparation.
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Description[Sar1, Ile8]-Angiotensin II is a peptide that has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels. The biological activities of angiotensin II antagonists upon basal and angiotensin II-stimulated aldosterone production were evaluated in an isolated canine glomerulosa cell preparation. (In Vitro):Angiotensin II has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels. Angiotensin II activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells.
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In VitroAngiotensin II has multiple effects on vascular smooth muscle, including contraction of normal arteries and hypertrophy or hyperplasia of cultured cells or diseased vessels. Angiotensin II activates both the NADPH and NADH oxidases, and stimulates superoxide anion formation in vascular smooth muscle cells.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number37827-06-8
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Formula Weight968.15
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Molecular FormulaC46H73N13O10
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameSequence:{SAR}-Arg-Val-Tyr-Ile-His-Pro-Ile
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Griendling KK, et al. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. Circ Res. 1994 Jun;74(6):1141-8.
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