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Allergen Gal d 4 (46-61), chicken
CAS No. 62982-31-4
Allergen Gal d 4 (46-61), chicken( Lysozyme C (46-61) (chicken) )
Catalog No. M29807 CAS No. 62982-31-4
Allergen Gal d 4 (46-61), chicken is a hen egg white lysozyme peptide.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameAllergen Gal d 4 (46-61), chicken
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NoteResearch use only, not for human use.
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Brief DescriptionAllergen Gal d 4 (46-61), chicken is a hen egg white lysozyme peptide.
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DescriptionAllergen Gal d 4 (46-61), chicken is a hen egg white lysozyme peptide.(In Vitro):Allergen Gal d 4 (46-61), chicken (HEL(46-61)) contains the immunodominant epitope recognized by mice of the k haplotype. The binding is shown to be specific, with a Kd of approximately 2 uM. The direct binding of a hen egg white lysozyme peptide, Allergen Gal d 4 (46-61), is examined to membrane I-Ak (protein encoded in the A locus of the I region) molecules in the presence of detergent. A number of synthetic peptide derivatives, which do not stimulate our T-cell reactive hybridomas, compete for the binding of Allergen Gal d 4 (46-61) to I-Ak and also inhibit the functional presentation of Allergen Gal d 4 (46-61). Inhibitors include a peptide lacking a tyrosine at position 53 and a peptide corresponding to the autologous lysozyme peptide. Presentation is examined with cells or with supported planar phospholipid membranes bearing only I-Ak and Allergen Gal d 4 (46-61).
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In VitroAllergen Gal d 4 (46-61), chicken (HEL(46-61)) contains the immunodominant epitope recognized by mice of the k haplotype. The binding is shown to be specific, with a Kd of approximately 2 uM. The direct binding of a hen egg white lysozyme peptide, Allergen Gal d 4 (46-61), is examined to membrane I-Ak (protein encoded in the A locus of the I region) molecules in the presence of detergent. A number of synthetic peptide derivatives, which do not stimulate our T-cell reactive hybridomas, compete for the binding of Allergen Gal d 4 (46-61) to I-Ak and also inhibit the functional presentation of Allergen Gal d 4 (46-61). Inhibitors include a peptide lacking a tyrosine at position 53 and a peptide corresponding to the autologous lysozyme peptide. Presentation is examined with cells or with supported planar phospholipid membranes bearing only I-Ak and Allergen Gal d 4 (46-61). T
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In Vivo——
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SynonymsLysozyme C (46-61) (chicken)
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PathwayGPCR/G Protein
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TargetAntibacterial
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number62982-31-4
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Formula Weight1753.82
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Molecular FormulaC72H116N22O29
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameSequence:Asn-Thr-Asp-Gly-Ser-Thr-Asp-Tyr-Gly-Ile-Leu-Gln-Ile-Asn-Ser-Arg
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Proc Natl Acad Sci U S A. 1986 Jun;83(12):4509-13.
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