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Amorolfine HCL
CAS No. 106614-68-0
Amorolfine HCL( —— )
Catalog No. M22881 CAS No. 106614-68-0
Amorolfine HCL is an antifungal reagent. It exerts the antifungal activity by selectively interrupting two steps in the pathway of ergosterol synthesis and eventually disrupting the function and structure of fungal cell membrane. Amorolfine, a morpholine antifungal drug, can inhibit D14 reductase and D7-D8 isomerase.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 45 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameAmorolfine HCL
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NoteResearch use only, not for human use.
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Brief DescriptionAmorolfine HCL is an antifungal reagent. It exerts the antifungal activity by selectively interrupting two steps in the pathway of ergosterol synthesis and eventually disrupting the function and structure of fungal cell membrane. Amorolfine, a morpholine antifungal drug, can inhibit D14 reductase and D7-D8 isomerase.
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DescriptionAmorolfine HCL is an antifungal reagent. It exerts the antifungal activity by selectively interrupting two steps in the pathway of ergosterol synthesis and eventually disrupting the function and structure of fungal cell membrane. Amorolfine, a morpholine antifungal drug, can inhibit D14 reductase and D7-D8 isomerase. These enzymes can deplete ergosterol and cause ignosterol to accumulate in the fungal cytoplasmic cell membranes.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibiotic
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Research AreaImmune system/Infection
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IndicationOnychomycosis
Chemical Information
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CAS Number106614-68-0
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Formula Weight354
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Molecular FormulaC21H36ClNO?
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Purity>98% (HPLC)
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SolubilityDMSO:12.5 mg/mL (35.31 mM; Need ultrasonic);H2O:3.33 mg/mL (9.41 mM; Need ultrasonic)
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SMILESCCC(C)(C)C1=CC=C(C=C1)CC(C)CN2CC(OC(C2)C)C.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Espinel-Ingroff A, et al. Antimicrob Agents ChemOthers. 1984 Jul; 26(1):5-9.
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