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α-Factor Mating Pheromone, yeast

CAS No. 59401-28-4

α-Factor Mating Pheromone, yeast( Mating Factor α )

Catalog No. M29805 CAS No. 59401-28-4

Alpha factor mating pheromone is a peptide of 13 amino acids secreted by Saccharomyces cerevisiae α cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    α-Factor Mating Pheromone, yeast
  • Note
    Research use only, not for human use.
  • Brief Description
    Alpha factor mating pheromone is a peptide of 13 amino acids secreted by Saccharomyces cerevisiae α cells.
  • Description
    Alpha factor mating pheromone is a peptide of 13 amino acids secreted by Saccharomyces cerevisiae α cells. (In Vitro):α-Factor Mating Pheromone, yeast is synthesized constitutively by MATα cells and acting on MATa cells. α-Factor Mating Pheromone, yeast inhibits the division cycle of yeast a cells, and competes for binding of 35S-α-factor to haploid a cells, with Kd of 0.3 μM, and this binding is related to five temperature-sensitive ste2 mutants, and is thermolabile. However, α-Factor Mating Pheromone, yeast binding activity of other temperature-sensitive mutants (ste4, ste5, ste7, ste11, and ste12) shows no thermolability.
  • In Vitro
    α-Factor Mating Pheromone, yeast is synthesized constitutively by MATα cells and acting on MATa cells. α-Factor Mating Pheromone, yeast inhibits the division cycle of yeast a cells, and competes for binding of 35S-α-factor to haploid a cells, with Kd of 0.3 μM, and this binding is related to five temperature-sensitive ste2 mutants, and is thermolabile. However, α-Factor Mating Pheromone, yeast binding activity of other temperature-sensitive mutants (ste4, ste5, ste7, ste11, and ste12) shows no thermolability.
  • In Vivo
    ——
  • Synonyms
    Mating Factor α
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Ste2p
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    59401-28-4
  • Formula Weight
    1684
  • Molecular Formula
    C82H114N20O17S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : 50 mg/mL (29.69 mM)
  • SMILES
    ——
  • Chemical Name
    Sequence:Trp-His-Trp-Leu-Gln-Leu-Lys-Pro-Gly-Gln-Pro-Met-Tyr

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Naider F, et al. The alpha-factor mating pheromone of Saccharomyces cerevisiae: a model for studying the interaction of peptide hormones and G protein-coupled receptors. Peptides. 2004 Sep;25(9):1441-63.
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