Cart
sales@molnova.com
LY450108
CAS No. 376594-67-1
LY450108( —— )
Catalog No. M29625 CAS No. 376594-67-1
LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 160 | Get Quote |
|
| 10MG | 260 | Get Quote |
|
| 25MG | 465 | Get Quote |
|
| 50MG | 673 | Get Quote |
|
| 100MG | 945 | Get Quote |
|
| 500MG | 1881 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameLY450108
-
NoteResearch use only, not for human use.
-
Brief DescriptionLY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.
-
DescriptionLY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.
-
In VitroAMPA receptors mediate most of the excitatory neurotransmission and play a key role in synaptic plasticity in the mammalian central nervous system (CNS). Recent evidence has shown that in addition to modulating fast synaptic plasticity and memory processes, AMPA receptor potentiators alter downstream signalling pathways and may thereby have utility in other CNS disorders.
-
In Vivo——
-
Synonyms——
-
PathwayMembrane Transporter/Ion Channel
-
TargetiGluR
-
RecptoriGluR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number376594-67-1
-
Formula Weight396.45
-
Molecular FormulaC19H22F2N2O3S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : ≥ 50 mg/mL (126.12 mM)
-
SMILESCC(C)S(NC[C@H](C)c(cc1)ccc1NC(c1cc(F)cc(F)c1)=O)(=O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog
related products
-
Becampanel
Becampanel (AMP 397) potent, competitive antagonist of the AMPA receptor (AMPAR) with IC50 of 11 nM.
-
Traxoprodil
A potent and NR2B-selective NMDA receptor antagonist; potently protects cultured hippocampal neurons from glutamate toxicity (IC50=10 nM).
-
GYKI 52466 dihydroch...
GYKI 52466 is a selective, non-competitive, orally active AMPA receptor (AMPAR) antagonist with IC50 of 10-20 uM against AMPA-induced responses.
