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MT-DADMe-ImmA
CAS No. 653592-04-2
MT-DADMe-ImmA( Methylthio-DADMe-Immucillin A | MTDIA )
Catalog No. M29593 CAS No. 653592-04-2
MT-DADMe-ImmA is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP, Ki: 90 pM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 163 | In Stock |
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| 5MG | 130 | In Stock |
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| 10MG | 225 | In Stock |
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| 25MG | 398 | In Stock |
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| 50MG | 548 | In Stock |
|
| 100MG | 770 | In Stock |
|
| 200MG | 1014 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMT-DADMe-ImmA
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NoteResearch use only, not for human use.
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Brief DescriptionMT-DADMe-ImmA is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP, Ki: 90 pM).
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DescriptionMT-DADMe-ImmA is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP, Ki: 90 pM).(In Vitro):Treatment of cultured cells with MTA and MT-DADMe-ImmA inhibit MTAP, increase cellular MTA concentrations, decrease polyamines, and induce apoptosis in FaDu and Cal27, two head and neck squamous cell carcinoma cell lines. MT-DADMe-ImmA alone does not induce apoptosis in any cell line .(In Vivo):MTAP activity slowly returns, giving a biological half-life for the action of oral MT-DADMe-ImmA of 6.3 days. The time-dependent growth of FaDu tumors in immunodeficient mice is suppressed by oral or intraperitoneal treatment with MT-DADMe-ImmA .
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In Vitro——
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In Vivo——
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SynonymsMethylthio-DADMe-Immucillin A | MTDIA
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number653592-04-2
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Formula Weight293.39
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Molecular FormulaC13H19N5OS
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (340.84 mM)
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SMILESCSC[C@H]1CN(Cc2c[nH]c3c(N)ncnc23)C[C@@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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