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Caulophyllogenin

CAS No. 52936-64-8

Caulophyllogenin( Segetalic acid )

Catalog No. M29110 CAS No. 52936-64-8

Caulophyllogenin is a partial PPARγ agonist (EC50 = 12.6 μM) derived from the stem bark of Kalopanax pictus (Araliaceae).

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Caulophyllogenin
  • Note
    Research use only, not for human use.
  • Brief Description
    Caulophyllogenin is a partial PPARγ agonist (EC50 = 12.6 μM) derived from the stem bark of Kalopanax pictus (Araliaceae).
  • Description
    Caulophyllogenin is a partial PPARγ agonist (EC50 = 12.6 μM) derived from the stem bark of Kalopanax pictus (Araliaceae). Caulophyllogenin inhibits pro-inflammatory cytokine secretion and can be used in studies about the prevention and treatment of inflammatory diseases, type-2 diabetes, obesity and metabolic syndrome.(In Vitro):Caulophyllogenin inhibits IL-12 p40, IL-6, and TNF-α with IC50s ranging from 3.3 to 20.0 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Segetalic acid
  • Pathway
    Apoptosis
  • Target
    IL Receptor
  • Recptor
    IL Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    52936-64-8
  • Formula Weight
    488.709
  • Molecular Formula
    C30H48O5
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    [H][C@@]12CC(C)(C)CC[C@@]1([C@H](O)C[C@]1(C)C2=CC[C@]2([H])[C@@]3(C)CC[C@H](O)[C@@](C)(CO)[C@]3([H])CC[C@@]12C)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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