GSK-1520489A

CAS No. 1042433-41-9

GSK-1520489A( —— )

Catalog No. M28990 CAS No. 1042433-41-9

GSK-1520489A is an active PKMYT1 inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 121 In Stock
10MG 188 In Stock
25MG 335 In Stock
50MG 460 In Stock
100MG 647 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    GSK-1520489A
  • Note
    Research use only, not for human use.
  • Brief Description
    GSK-1520489A is an active PKMYT1 inhibitor.
  • Description
    GSK-1520489A is an active PKMYT1 inhibitor.
  • In Vitro
    GSK-1520489A (4 μM, 24 h) treatment shows inhibition of phosphorylation of Tyr15 in Cdk1. Western Blot Analysis Cell Line:HT29 cells Concentration:4 μM Incubation Time:24 hours Result:Reduced Cdk1-phosphorylation at tyrosine in comparison to the uninhibited reaction.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    MCT4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1042433-41-9
  • Formula Weight
    538.53
  • Molecular Formula
    C21H23N4O7PS2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 35.71 mg/mL (83.92 mM)
  • SMILES
    CC(C)(C)S(c1cc2c(Nc(cc3)cc4c3scn4)ncnc2cc1OCCOP(O)(O)=O)(=O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Cluntun AA, et.al. The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure. Cell Metab. 2021 Mar 2;33(3):629-648.e10.
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