Cart
sales@molnova.com
4-Octyl itaconate
CAS No. 3133-16-2
4-Octyl itaconate( 4-Octyl Itaconate | 4 Octyl Itaconate | 4-Octyl-Itaconate )
Catalog No. M18412 CAS No. 3133-16-2
4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 38 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name4-Octyl itaconate
-
NoteResearch use only, not for human use.
-
Brief Description4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
-
Description4-Octyl Itaconate is a cell permeable activator of Nrf2 which inhibits LPS-induced increases in IL-1β mRNA, HIF-1α, and IL-10 in macrophages.
-
In Vitro——
-
In Vivo——
-
Synonyms4-Octyl Itaconate | 4 Octyl Itaconate | 4-Octyl-Itaconate
-
PathwayOthers
-
TargetOther Targets
-
RecptorKeap1-Nrf2
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number3133-16-2
-
Formula Weight242.31
-
Molecular FormulaC13H22O4
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 150 mg/mL; 619.04 mM
-
SMILESCCCCCCCCOC(=O)CC(=C)C(O)=O
-
Chemical Name2-Methylene-4-(octyloxy)-4-oxobutanoic acid
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Mills EL, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature. 2018 Apr 5;556(7699):113-117.
molnova catalog
related products
-
(-)-Dihydrocarveol
(-)-Dihydrocarveol has anti-inflammatory activity, Insecticidal activity, and it's monoterpenoid agonists of TRPV3.
-
AZM475271
AZM475271 is a potent and selective inhibitor of Src kinase (IC50: 5 nM).
-
Prolylleucine
Prolylleucine is a dipeptide containing branched-chain amino acids.
