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4-Octyl itaconate

CAS No. 3133-16-2

4-Octyl itaconate( 4-Octyl Itaconate | 4 Octyl Itaconate | 4-Octyl-Itaconate )

Catalog No. M18412 CAS No. 3133-16-2

4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	42	In Stock
25MG	29	In Stock
50MG	37	In Stock
100MG	54	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

4-Octyl itaconate
Note

Research use only, not for human use.
Brief Description

4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
Description

4-Octyl Itaconate is a cell permeable activator of Nrf2 which inhibits LPS-induced increases in IL-1β mRNA, HIF-1α, and IL-10 in macrophages.
In Vitro

——
In Vivo

——
Synonyms

4-Octyl Itaconate | 4 Octyl Itaconate | 4-Octyl-Itaconate
Pathway

Others
Target

Other Targets
Recptor

Keap1-Nrf2
Research Area

——
Indication

——

Chemical Information

CAS Number

3133-16-2
Formula Weight

242.31
Molecular Formula

C13H22O4
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 150 mg/mL; 619.04 mM
SMILES

CCCCCCCCOC(=O)CC(=C)C(O)=O
Chemical Name

2-Methylene-4-(octyloxy)-4-oxobutanoic acid

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Mills EL, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature. 2018 Apr 5;556(7699):113-117.

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