PARP1-IN-8?

Research use only, not for human use.

PARP1-IN-8 is an effective inhibito of PARP1 (IC50 = 97 nM).

PARP1-IN-8 is an effective inhibito of PARP1 (IC50 = 97 nM).(In Vitro):PARP1-IN-8 (0, 0.1, 1, 10 μM; 24, 48 h) showed significantly potent anti-proliferative activity against A549 cells and didn’t display any significant cytotoxicity on HFF cells.

PARP1-IN-8 (compound 11c) (0-10 μM, 24-48 h) shows significantly potent anti-proliferative activity against A549 cells. Cell Proliferation Assay Cell Line:A549, HFF cells Concentration:0, 0.1, 1, 10 μM Incubation Time:24, 48 h Result:Showed significantly potent anti-proliferative activity against A549 cells, and didn’t display any significant cytotoxicity on HFF cells.

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N-(3-chlorophenyl)-3-(1-oxo-4-phenylphthalazin-2(1H)-yl)propanamide

Cell Cycle/DNA Damage

PARP

BRD4

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836640-15-4

403.87

C23H18ClN3O2

>98% (HPLC)

In Vitro:?DMSO : 62.5 mg/mL (154.76 mM)

Clc1cccc(NC(=O)CCn2nc(-c3ccccc3)c3ccccc3c2=O)c1

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(-20℃)

With Ice Pack

≥ 2 years