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(E)-SI-2
CAS No. 380537-35-9
(E)-SI-2( —— )
Catalog No. M28929 CAS No. 380537-35-9
(E)-SI-2 is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 136 | In Stock |
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| 5MG | 134 | In Stock |
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| 10MG | 199 | In Stock |
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| 25MG | 316 | In Stock |
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| 50MG | 442 | In Stock |
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| 100MG | 593 | In Stock |
|
| 200MG | 775 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name(E)-SI-2
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NoteResearch use only, not for human use.
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Brief Description(E)-SI-2 is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2.
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Description(E)-SI-2 is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2. It selectively reduces cellular protein levels of SRC-3, but not that of CARM-1, blocks MDA-MB-468 cell growth with an IC50 value of 3.4 nM, but spares normal cells.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorAntibacterial
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Research Area——
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Indication——
Chemical Information
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CAS Number380537-35-9
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Formula Weight265.31
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Molecular FormulaC15H15N5
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Purity>98% (HPLC)
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Solubility——
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SMILESCN1C2=CC=CC=C2N=C1N/N=C(C3=NC=CC=C3)\C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Laetrile
Laetrile is a glycoside initially isolated from the seeds of the tree Prunus dulcis, also known as bitter almonds.
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1,1'-(4-CHLOROBUTYLI...
1,1'-(4-Chlorobutylidene)bis(4-fluorobenzene) is a derivative of Zerumbone with potential anti-tumor effects towards HeLa cancer cells.
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(Pyr5,N-Me-Phe8,Sar9...
[Glp5,(Me)Phe8,Sar9] Substance P (5-11) (DiMe-C7) is a Substance P analogue that has approximately the same effects as Substance P on neurokinin 1 receptor (NK1R) in rat brain, but with a much longer duration of action. [Glp5,(Me)Phe8,Sar9] Substance P (5-11) selectively activates dopamine metabolism in the mesencephalon and midbrain cortex of the rat brain. [Glp5,(Me)Phe8,Sar9] Substance P (5-11) also increases motor activity and induces recovery of addictive agent-seeking behavior in rats.
