Cevidoplenib dimesylate hydrochloride

Research use only, not for human use.

Cevidoplenib dimesylate hydrochloride is a spleen tyrosine kinase (Syk) inhibitor showing potential immunomodulating and anti-inflammatory properties.

Cevidoplenib dimesylate hydrochloride is a spleen tyrosine kinase (Syk) inhibitor showing potential immunomodulating and anti-inflammatory properties.(In Vitro):Cevidoplenib dimesylate hydrochloride(oral) inhibited the activity of SYK and blocked Fc receptor and B-cell receptor (BCR)-mediated signaling in inflammatory cells, including macrophages, mast cells, natural killer cells, B cells, and neutrophils.

——

——

Cevidoplenib dimesylate hydrochloride(2043659-93-2 Free base)

Angiogenesis

Syk

Adenylyl cyclase (AC)

——

——

269062-93-3

1957.9

C90H132Cl5N27O12

>98% (HPLC)

——

NCCCC[C@@H](C(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H]3N(C([C@H](CC4=CNC5=C4C=CC=C5)NC([C@H](CC6=CNC7=C6C=CC=C7)NC([C@H]8N(C([C@H](CC9=CNC%10=C9C=CC=C%10)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)N)=

——

(-20℃)

With Ice Pack

≥ 2 years