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Cevidoplenib dimesylate hydrochloride

CAS No. 269062-93-3

Cevidoplenib dimesylate hydrochloride( Cevidoplenib dimesylate hydrochloride(2043659-93-2 Free base) )

Catalog No. M28906 CAS No. 269062-93-3

Cevidoplenib dimesylate hydrochloride is a spleen tyrosine kinase (Syk) inhibitor showing potential immunomodulating and anti-inflammatory properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 223 Get Quote
10MG 357 Get Quote
25MG 597 Get Quote
50MG 851 Get Quote
100MG 1152 Get Quote
500MG 2313 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Cevidoplenib dimesylate hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Cevidoplenib dimesylate hydrochloride is a spleen tyrosine kinase (Syk) inhibitor showing potential immunomodulating and anti-inflammatory properties.
  • Description
    Cevidoplenib dimesylate hydrochloride is a spleen tyrosine kinase (Syk) inhibitor showing potential immunomodulating and anti-inflammatory properties.(In Vitro):Cevidoplenib dimesylate hydrochloride(oral) inhibited the activity of SYK and blocked Fc receptor and B-cell receptor (BCR)-mediated signaling in inflammatory cells, including macrophages, mast cells, natural killer cells, B cells, and neutrophils.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Cevidoplenib dimesylate hydrochloride(2043659-93-2 Free base)
  • Pathway
    Angiogenesis
  • Target
    Syk
  • Recptor
    Adenylyl cyclase (AC)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    269062-93-3
  • Formula Weight
    1957.9
  • Molecular Formula
    C90H132Cl5N27O12
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    NCCCC[C@@H](C(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H]3N(C([C@H](CC4=CNC5=C4C=CC=C5)NC([C@H](CC6=CNC7=C6C=CC=C7)NC([C@H]8N(C([C@H](CC9=CNC%10=C9C=CC=C%10)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)N)=
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ramos-Espiritu L, et al. Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase. Nat Chem Biol. 2016 Oct;12(10):838-44.
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    Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.