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20-(tert-Butoxy)-20-oxoicosanoic acid
CAS No. 683239-16-9
20-(tert-Butoxy)-20-oxoicosanoic acid( —— )
Catalog No. M28903 CAS No. 683239-16-9
20-(tert-Butoxy)-20-oxoicosanoic acid is a alkyl-chain-based PROTAC linker. 20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 45 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name20-(tert-Butoxy)-20-oxoicosanoic acid
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NoteResearch use only, not for human use.
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Brief Description20-(tert-Butoxy)-20-oxoicosanoic acid is a alkyl-chain-based PROTAC linker. 20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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Description20-(tert-Butoxy)-20-oxoicosanoic acid is a alkyl-chain-based PROTAC linker. 20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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In VitroADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorGABA Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number683239-16-9
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Formula Weight398.628
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Molecular FormulaC24H46O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)(C)OC(=O)CCCCCCCCCCCCCCCCCCC(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Manev H, et al. Progabide, a GABA mimetic drug, stimulates the secretion of plasma corticosterone in rats. Pharmacol Biochem Behav. 1987 Dec;28(4):443-6.
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