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TL-895
CAS No. 1415823-49-2
TL-895( —— )
Catalog No. M28845 CAS No. 1415823-49-2
TL-895 is an ATP-competitive, and highly selective irreversible inhibitor of Bruton’s Tyrosine Kinase(BTK). TL-895 showed good potency with an IC50 of 1.5 nM and a Ki of 11.9 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 55 | In Stock |
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| 2MG | 33 | In Stock |
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| 5MG | 55 | In Stock |
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| 10MG | 89 | In Stock |
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| 25MG | 181 | In Stock |
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| 50MG | 275 | In Stock |
|
| 100MG | 405 | In Stock |
|
| 200MG | 574 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTL-895
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NoteResearch use only, not for human use.
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Brief DescriptionTL-895 is an ATP-competitive, and highly selective irreversible inhibitor of Bruton’s Tyrosine Kinase(BTK). TL-895 showed good potency with an IC50 of 1.5 nM and a Ki of 11.9 nM.
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DescriptionTL-895 is an ATP-competitive, and highly selective irreversible inhibitor of Bruton’s Tyrosine Kinase(BTK). TL-895 showed good potency with an IC50 of 1.5 nM and a Ki of 11.9 nM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayTyrosine Kinase
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TargetBTK
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number1415823-49-2
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Formula Weight447.5
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Molecular FormulaC25H26FN5O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (558.66 mM)
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SMILESC=CC(N(CC1)CCC1(CNc1ncnc(N)c1-c(cc1)ccc1Oc1ccccc1)F)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Meier, U.T., Kronbach, T., and Meyer, U.A. Assay of mephenytoin metabolism in human liver microsomes by high-performance liquid chromatography. Anal. Biochem. 151(2), 286-291 (1985).
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