β-catenin-IN-2( —— )

Catalog No. M28838 CAS No. 1458664-10-2

β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	264	In Stock
5MG	227	In Stock
10MG	359	In Stock
25MG	607	In Stock
50MG	849	In Stock
100MG	1144	In Stock
200MG	Get Quote	In Stock
500MG	2316	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

β-catenin-IN-2
Note

Research use only, not for human use.
Brief Description

β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.
Description

β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.(In Vitro):In HCT116 cells, β-catenin-IN-2 (10-40 μM) dose-dependently suppressed the transcriptional activity of the β-catenin/Tcf-4 .
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Wnt/Notch/Hedgehog
Target

Wnt/beta/catenin
Recptor

H4 receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

1458664-10-2
Formula Weight

255.29
Molecular Formula

C15H14FN3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 83.33 mg/mL (326.41 mM)
SMILES

CN(C)c(cc1)ccc1-c1nc(ccc(F)c2)c2[nH]1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Sanna MD, et al. Histamine H4 receptor stimulation in the locus coeruleus attenuates neuropathic pain by promoting the coeruleospinal noradrenergic inhibitory pathway. Eur J Pharmacol. 2020 Feb 5;868:172859.

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