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β-catenin-IN-2
CAS No. 1458664-10-2
β-catenin-IN-2( —— )
Catalog No. M28838 CAS No. 1458664-10-2
β-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 264 | In Stock |
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| 5MG | 227 | In Stock |
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| 10MG | 359 | In Stock |
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| 25MG | 607 | In Stock |
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| 50MG | 849 | In Stock |
|
| 100MG | 1144 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 2316 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Nameβ-catenin-IN-2
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NoteResearch use only, not for human use.
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Brief Descriptionβ-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.
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Descriptionβ-catenin-IN-2 is a potent inhibitor of β-catenin that can be used in colorectal cancer research.(In Vitro):In HCT116 cells, β-catenin-IN-2 (10-40 μM) dose-dependently suppressed the transcriptional activity of the β-catenin/Tcf-4 .
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayWnt/Notch/Hedgehog
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TargetWnt/beta/catenin
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RecptorH4 receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1458664-10-2
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Formula Weight255.29
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Molecular FormulaC15H14FN3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 83.33 mg/mL (326.41 mM)
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SMILESCN(C)c(cc1)ccc1-c1nc(ccc(F)c2)c2[nH]1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sanna MD, et al. Histamine H4 receptor stimulation in the locus coeruleus attenuates neuropathic pain by promoting the coeruleospinal noradrenergic inhibitory pathway. Eur J Pharmacol. 2020 Feb 5;868:172859.
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