BMS986299

CAS No. 2242952-69-6

BMS986299( Unii-VS58MO4P47 )

Catalog No. M28769 CAS No. 2242952-69-6

BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 93 In Stock
5MG 85 In Stock
10MG 140 In Stock
25MG 282 In Stock
50MG 445 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    BMS986299
  • Note
    Research use only, not for human use.
  • Brief Description
    BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.
  • Description
    BMS986299 is a modulator of NLRP3 with an EC50 of 1.28 μM and can be used in studies about NLRP3 signaling and the treatment of associated diseases.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Unii-VS58MO4P47
  • Pathway
    NF-κB
  • Target
    NOD
  • Recptor
    Cationic Lipid
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2242952-69-6
  • Formula Weight
    349.39
  • Molecular Formula
    C18H19N7O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 33.33 mg/mL (95.39 mM)
  • SMILES
    O=C(N(CC1=NC=2C(=NC=3C=C(C=CC3C2N1)C4=NNC=C4)N)CC)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Aime S, et al. Properties, solution state behavior, and crystal structures of chelates of DOTMA. Inorg Chem. 2011;50(17):7955-7965.
molnova catalog
related products
  • NLRP3-IN-9

    NLRP3-IN-9 is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner.

  • NT-0796

    NT-0796 is a brain-permeable, potent, and selective inhibitor of the inflammasome NLRP3, inhibiting NLRP3 activation.NT-0796 is a potential NDT-19795 delivery vector.

  • antcin A

    antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and anti-tumor effects.