Pomalidomide 4'-PEG2-azide?( 4-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione )

Catalog No. M28652 CAS No. 2271036-45-2

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Product Name

Pomalidomide 4'-PEG2-azide?
Note

Research use only, not for human use.
Brief Description

Pomalidomide 4'-PEG2-azide is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a linker.
Description

Pomalidomide 4'-PEG2-azide is a synthetic E3 ligase ligand-linker conjugate containing a Pomalidomide-based cereblon ligand and a linker.(In Vitro):PROTACs contain two different ligands, linked by a linker; one of them is a ligand for E3 ubiquitin ligase and the other is a ligand for the target protein.
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

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Synonyms

4-((2-(2-(2-azidoethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
Pathway

Others
Target

Other Targets
Recptor

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Research Area

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Indication

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1.Khare P, et al. Development of Lipidoid Nanoparticles for siRNA Delivery to Neural Cells. AAPS J. 2021;24(1):8. Published 2021 Dec 6.

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