IU1-248( —— )

Catalog No. M28642 CAS No. 2307472-03-1

IU1-248 is a derivative of IU1. IU1-248 is a potent and selective USP14 inhibitor with an IC50 of 0.83 μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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5MG	155	Get Quote
10MG	250	Get Quote
25MG	507	Get Quote
50MG	714	Get Quote
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Biological Information

Product Name

IU1-248
Note

Research use only, not for human use.
Brief Description

IU1-248 is a derivative of IU1. IU1-248 is a potent and selective USP14 inhibitor with an IC50 of 0.83 μM.
Description

IU1-248 is a derivative of IU1. IU1-248 is a potent and selective USP14 inhibitor with an IC50 of 0.83 μM.(In Vitro):IU1-248 exhibits an IC50 value of 0.83 μM toward USP14, which is 10-fold more potent than that of IU1 (IC50=12.25 μM).
In Vitro

IU1-248 exhibits an IC50 value of 0.83?μM toward USP14, which is comparable to that of IU1-47 (IC50=0.68 μM) and 10-fold more potent than that of IU1 (IC50=12.25 μM).
In Vivo

——
Synonyms

——
Pathway

Proteasome/Ubiquitin
Target

DUB
Recptor

H1 receptor|Human Endogenous Metabolite|K+ current (IKr)|Cholinergic
Research Area

——
Indication

——

Chemical Information

CAS Number

2307472-03-1
Formula Weight

337.42
Molecular Formula

C20H23N3O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 83.33 mg/mL (246.96 mM)
SMILES

Cc1cc(C(CN(CC2)CCC2O)=O)c(C)n1-c(cc1)ccc1C#N
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Sakuta H. Inhibition by histamine H1 receptor antagonists of endogenous glibenclamide-sensitive K+ channels in follicle-enclosed Xenopus oocytes. Eur J Pharmacol. 1994 Jan 1;266(1):99-102.

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