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DL-Pyroglutamic acid
CAS No. 149-87-1
DL-Pyroglutamic acid( —— )
Catalog No. M28638 CAS No. 149-87-1
DL-Pyroglutamic acid exhibited a strong inactivating effect on hepatitis B surface antigen.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 29 | In Stock |
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| 5MG | 49 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDL-Pyroglutamic acid
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NoteResearch use only, not for human use.
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Brief DescriptionDL-Pyroglutamic acid exhibited a strong inactivating effect on hepatitis B surface antigen.
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DescriptionDL-Pyroglutamic acid exhibited a strong inactivating effect on hepatitis B surface antigen.
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In VitroDL-Pyroglutamic acid results 50 and 100% inactivation of the antigen of 0.01-0.025% and 0.025-0.05%, respectively.DL-Pyroglutamic acid is a possible glutamate antagonist, blocks glutamate miniature-end-plate potential in locust muscle-Druce and Bradford.
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In VivoDL-Pyroglutamic acid (0.775 mM/L) completely abolishes the myoclonic jerks and EEG spikes in rats model of epileptic by cobalt implantation in the sensorimotor cerebral cortex.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorPyroptosis|Caspase-1|IL-1β|inflammation
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Research Area——
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Indication——
Chemical Information
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CAS Number149-87-1
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Formula Weight129.114
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Molecular FormulaC5H7NO3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (774.53 mM)
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SMILESO=C(O)C(CC1)NC1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Rabuffetti, M., Sciorati, C., Tarozzo, G., et al. Inhibition of caspase-1-like activity by Ac-Tyr-Val-Ala-Asp-chloromethyl ketone induces long-lasting neuroprotection in cerebral ischemia through apoptosis reduction and decrease of proinflammatory cytokines. Journal of Neuroscience 20, 4398-4404 (2000).
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