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Nirmatrelvir
CAS No. 2628280-40-8
Nirmatrelvir( PF-07321332 )
Catalog No. M28623 CAS No. 2628280-40-8
PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 129 | In Stock |
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| 2MG | 71 | In Stock |
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| 5MG | 117 | In Stock |
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| 10MG | 187 | In Stock |
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| 25MG | 332 | In Stock |
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| 50MG | 501 | In Stock |
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| 100MG | 648 | In Stock |
|
| 200MG | 925 | In Stock |
|
| 500MG | 1386 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNirmatrelvir
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NoteResearch use only, not for human use.
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Brief DescriptionPF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) .
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DescriptionPF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) .(In Vitro):PF-07321332 is a promising oral antiviral clinical candidate with well-established anti-SARS-CoV-2 activity in vitro.(In Vitro):3CLPRO is responsible for cleaving polyproteins 1a and 1ab of SARS-CoV-2.1. Without the activity of the SARS-CoV-2 3CLPRO, nonstructural proteins (including proteases) cannot be released to perform their functions, inhibiting viral replication.
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In Vitro——
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In Vivo——
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SynonymsPF-07321332
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PathwayOthers
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TargetOther Targets
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number2628280-40-8
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Formula Weight499.53
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Molecular FormulaC23H32F3N5O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 140 mg/mL (280.26 mM)
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SMILESCC(C)(C)[C@@H](C(N(C[C@@H]1C(C)(C)[C@H]11)[C@@H]1C(N[C@@H](C[C@H](CCN1)C1=O)C#N)=O)=O)NC(C(F)(F)F)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kida M, et al. Pseudorotaxanes in the gas phase: structure and energetics of protonated dibenzylamine-crown ether complexes. Phys Chem Chem Phys. 2018 Jun 29.
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