Cart
sales@molnova.com
CVN424
CAS No. 2254706-21-1
CVN424( —— )
Catalog No. M28619 CAS No. 2254706-21-1
CVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 249 | In Stock |
|
| 5MG | 236 | In Stock |
|
| 10MG | 376 | In Stock |
|
| 25MG | 620 | In Stock |
|
| 50MG | 877 | In Stock |
|
| 100MG | 1144 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCVN424
-
NoteResearch use only, not for human use.
-
Brief DescriptionCVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.
-
DescriptionCVN424 is a selective and novel GPR6 Inverse agonist effective in models of Parkinson Disease.(In Vivo): CVN424 is brain-penetrant and shows dose-dependent receptor occupancy that attained brain 50% of receptor occupancy at plasma concentrations of 6.0 and 7.4 ng/ml in mice and rats, respectively.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetGPR
-
Recptor5-HT4
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2254706-21-1
-
Formula Weight473.52
-
Molecular FormulaC24H29F2N5O3
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 62.5 mg/mL (131.99 mM)
-
SMILESCC(N(CC1)Cc(nc2N[C@H]3COCC3)c1nc2N(CC1)CCC1Oc(ccc(F)c1)c1F)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.R M Eglen, et al. Pharmacological characterization of two novel and potent 5-HT4 receptor agonists, RS 67333 and RS 67506, in vitro and in vivo. Br J Pharmacol. 1995 Aug;115(8):1387-92.
molnova catalog
related products
-
Acifran
Acifran (AY 25712) is an HM74A/GPR109A and GPR109B agonist and displays antihyperlipidemic activity.
-
GLPG1205
GLPG1205 is a potent, orally active GPR84 (G protein-coupled receptor) antagonist with anti-inflammatory activity. GLPG1205 shows good PK/PD characteristics and can be used to study pulmonary fibrosis.
-
Azathioprine
Azathioprine is an immunosuppressive drug, inhibiting purine synthesis and GTP-binding protein Rac1 activation, used in the treatment of organ transplantation and autoimmune diseases.
