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Thalidomide-O-amido-C3-NH2 TFA

CAS No. 2022182-58-5

Thalidomide-O-amido-C3-NH2 TFA( Cereblon Ligand-Linker Conjugates 16 TFA | E3 Ligase Ligand-Linker Conjugates 52 TFA )

Catalog No. M28569 CAS No. 2022182-58-5

Thalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Thalidomide-O-amido-C3-NH2 TFA
  • Note
    Research use only, not for human use.
  • Brief Description
    Thalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
  • Description
    Thalidomide-O-amido-C3-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Cereblon Ligand-Linker Conjugates 16 TFA | E3 Ligase Ligand-Linker Conjugates 52 TFA
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    platelet-activating factor (PAF)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2022182-58-5
  • Formula Weight
    502.403
  • Molecular Formula
    C20H21F3N4O8
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (248.81 mM)
  • SMILES
    OC(=O)C(F)(F)F.NCCCNC(=O)COc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Rylander R, et al. Modulation of pulmonary inflammation after endotoxin inhalation with a platelet-activating factor antagonist (48740 RP). Int Arch Allergy Appl Immunol. 1988;86(3):303-7.
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