Thiazolyl Blue( —— )

Catalog No. M21733 CAS No. 298-93-1

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Thiazolyl Blue
Note

Research use only, not for human use.
Brief Description

Thiazolyl Blue (MTT) is used in conjunction with rhodamine B to measure mitochondrial membrane potential.
Description

Thiazolyl Blue (MTT) is used in conjunction with rhodamine B to measure mitochondrial membrane potential. Thiazolyl Blue-formazan is generated in mitochondria acts as a fluorescence quencher for rhodamine that distributes across membranes of viable cells according to membrane potential. In the absence of mPMS, cellular reduction of Thiazolyl Blue is strong. Thiazolyl Blue is membrane-impermeable when incorporated into large unilamellar liposomes, and therefore it is taken up by cells via endocytosis.
In Vitro

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In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

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Research Area

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Indication

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CAS Number

298-93-1
Formula Weight

414.32
Molecular Formula

C??H??BrN?S
Purity

>98% (HPLC)
Solubility

DMSO : 25 mg/mL (60.34 mM; Need ultrasonic);H2O : 0.88 mg/mL (2.12 mM; Need ultrasonic and warming)
SMILES

CC1=C(C)N=C(N2N=C(C3=CC=CC=C3)N=[N+]2C4=CC=CC=C4)S1.[Br-]
Chemical Name

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1. Berridge MV, et al. Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction. Biotechnol Annu Rev. 2005;11:127-52.

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