Cart
sales@molnova.com
TIQ-A
CAS No. 420849-22-5
TIQ-A( —— )
Catalog No. M28456 CAS No. 420849-22-5
TIQ-A is a PARP1 inhibitor which involved in DNA single-strand break repair via the base excision repair pathway. PARP1 is triggered by DNA damage and its excessive activation has been proposed as a causative factor in many pathological conditions including ischemia and reperfusion injury, asthma-related inflammation, and atherogenesis.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 98 | In Stock |
|
| 5MG | 93 | In Stock |
|
| 10MG | 164 | In Stock |
|
| 25MG | 307 | In Stock |
|
| 50MG | 429 | In Stock |
|
| 100MG | 551 | In Stock |
|
| 200MG | 761 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameTIQ-A
-
NoteResearch use only, not for human use.
-
Brief DescriptionTIQ-A is a PARP1 inhibitor which involved in DNA single-strand break repair via the base excision repair pathway. PARP1 is triggered by DNA damage and its excessive activation has been proposed as a causative factor in many pathological conditions including ischemia and reperfusion injury, asthma-related inflammation, and atherogenesis.
-
DescriptionTIQ-A is a PARP1 inhibitor which involved in DNA single-strand break repair via the base excision repair pathway. PARP1 is triggered by DNA damage and its excessive activation has been proposed as a causative factor in many pathological conditions including ischemia and reperfusion injury, asthma-related inflammation, and atherogenesis.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetPARP
-
RecptorErα|NF-κB
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number420849-22-5
-
Formula Weight201.24
-
Molecular FormulaC11H7NOS
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 125 mg/mL (621.15 mM)
-
SMILESO=c1[nH]c2sccc2c2ccccc12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog
related products
-
GeA-69
GeA-69 (GeA69) is a selective and allosteric PARP14 macrodomain 2 (MD2) inhibitor (Kd: 0.86 μM in ITC assays).
-
RBN-3143
RBN-3143 is a potent inhibitor of NAD+-competitive catalytic PARP14 (IC50= 4 nM), which inhibits ADP-ribosylation mediated by PARP14 and stabilizes PARP14 in cell lines, demonstrating research potential for lung inflammation.
-
Gemcabene calcium
Gemcabene (PD-72953, PD72953) is a first-in-class lipid-lowering agent and activator of PARP.
