Cart
sales@molnova.com
Nicotredole
CAS No. 29876-14-0
Nicotredole( Tryptamide )
Catalog No. M28294 CAS No. 29876-14-0
Nicotredole (Tryptamide) is an orally active anti-inflammatory and analgesic agent. Nicotredole exhibits evident antiinflammatory effects of potency comparable with Phenylbutazone. Nicotredole has only weak ulcerogenic activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
|
| 5MG | 36 | In Stock |
|
| 10MG | 56 | In Stock |
|
| 25MG | 92 | In Stock |
|
| 50MG | 133 | In Stock |
|
| 100MG | 198 | In Stock |
|
| 200MG | 296 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNicotredole
-
NoteResearch use only, not for human use.
-
Brief DescriptionNicotredole (Tryptamide) is an orally active anti-inflammatory and analgesic agent. Nicotredole exhibits evident antiinflammatory effects of potency comparable with Phenylbutazone. Nicotredole has only weak ulcerogenic activity.
-
DescriptionNicotredole (Tryptamide) is an orally active anti-inflammatory and analgesic agent. Nicotredole exhibits evident antiinflammatory effects of potency comparable with Phenylbutazone. Nicotredole has only weak ulcerogenic activity.(In Vitro):Nicotredole inhibits prostaglandin synthetase activity in vitro . (In Vivo):Nicotredole produces antiinflammatory effects in carrageenin-induced rat paw oedema . Nicotredole reverses pyrogen-induced hyperthermia in rats, elicits analgesic effects in rats, prolongs the time of hexobarbital sleep in rats and inhibits locomotor activity in rats and mice . Nicotredole (i.p.) has LD50s of 1260 mg/kg and 1980 mg/kg for male rats and male mice, respectively . Nicotredole (p.o.) has LD50s of 8.5 g/kg and 9.3 g/kg for male rats and male mice, respectively . Nicotredole (25 mg/kg; p.o. or i.p.) undergoes fast absorption (t 1/2 =4.92-17.5 min) and elimination (t 1/2 =55.72-74.52 min), can reach C max (11-13 μg/cm 3 ) after 30 min, and gives AUC values in the range of 21.40-27.30 (μgh/cm 3 ) .
-
In Vitro——
-
In Vivo——
-
SynonymsTryptamide
-
PathwayOthers
-
TargetOther Targets
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number29876-14-0
-
Formula Weight265.316
-
Molecular FormulaC16H15N3O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(NCCc1c[nH]c2ccccc12)c1cccnc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Barlow RB, Burston KN. A comparison of cinobufotenine (the quaternary derivative of 5-HT) and some related compounds with coryneine (the quaternary derivative of dopamine) on the frog rectus, guinea-pig ileum and rat fundus strip preparations. Br J Pharmacol. 1980 Aug;69(4):597-600.
molnova catalog
related products
-
Chromostatin, bovine
Chromostatin bovine is a chromogranin A (CGA) derivative peptide, which inhibits postassium or carbamoylcholine induced catecholamine release with an ID50 of 5 nM. Chromostatin bovine reduces calcium flux, enhances the desensitization process of the cholinergic-evoked secretory response and modulates the endocrine response associated with catecholamine.
-
JK-P3
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays.
-
L-Dihydroorotic acid
L-Dihydroorotic acid also known as (S)-45-dihydroorotate or dihydro-L-orotate belongs to the class of organic compounds known as alpha amino acids and derivatives.
