Cart
sales@molnova.com
Home - Products - Membrane Transporter/Ion Channel - TRP/TRPV Channel - Evifacotrep

Evifacotrep

CAS No. 2413739-88-3

Evifacotrep( —— )

Catalog No. M28273 CAS No. 2413739-88-3

Evifacotrep, a short transient receptor potential channel 5 ( TRPC5 ) antagonist (WO2020061162, compound 100), can be used for the research of neurological diseases .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 155 In Stock
5MG 188 In Stock
10MG 302 In Stock
25MG 465 In Stock
50MG 677 In Stock
100MG 1004 In Stock
200MG 1516 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Evifacotrep
  • Note
    Research use only, not for human use.
  • Brief Description
    Evifacotrep, a short transient receptor potential channel 5 ( TRPC5 ) antagonist (WO2020061162, compound 100), can be used for the research of neurological diseases .
  • Description
    Evifacotrep, a short transient receptor potential channel 5 ( TRPC5 ) antagonist (WO2020061162, compound 100), can be used for the research of neurological diseases .(In Vitro):Evifacotrep is a short transient receptor potential channel 5 ( TRPC5 ) antagonist.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    TRP/TRPV Channel
  • Recptor
    Raf|KRAS
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2413739-88-3
  • Formula Weight
    441.77
  • Molecular Formula
    C18H12ClF4N5O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (113.18 mM)
  • SMILES
    O=C1NN=CC(N2Cc3ncnc(Oc(cc4)c(C(F)(F)F)cc4F)c3CC2)=C1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Huestis MP, et al. Targeting KRAS Mutant Cancers via Combination Treatment: Discovery of a Pyridopyridazinone pan-RAF Kinase Inhibitor. ACS Med Chem Lett. 2021 Apr 21;12(5):791-797.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • AMG-0347

    AMG-0347 (UNII-CD7L9290QR) is a small molecule inhibitor targeting TRPA1(transient receptor potential ankyrin 1) ion channels, a receptor found in sensory neurons and involved in the detection of pain and environmental stimuli. AMG-0347 acts by blocking the function of TRPA1 and has analgesic effects.

  • A-967079

    A potent, selective TRPA1 channel blocker with IC50 of 51 nM and 101 nM for hTRPA1 and rTRPA1, respectively.

  • AC1903

    AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss.AC1903, that specifically blocks TRPC5 channel activity in glomeruli of proteinuric rats.?

Sign In Join Free