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Pomalidomide-PEG4-C2-NH2 hydrochloride
CAS No. 2357105-92-9
Pomalidomide-PEG4-C2-NH2 hydrochloride( —— )
Catalog No. M28272 CAS No. 2357105-92-9
Pomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 46 | Get Quote |
|
| 25MG | 77 | Get Quote |
|
| 50MG | 125 | Get Quote |
|
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NamePomalidomide-PEG4-C2-NH2 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionPomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used to synthesize PROTACs.
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DescriptionPomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker that can be used to synthesize PROTACs.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorSOS1
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Research Area——
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Indication——
Chemical Information
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CAS Number2357105-92-9
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Formula Weight528.98
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Molecular FormulaC23H33ClN4O8
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 220 mg/mL (415.89 mM)
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SMILESO=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCOCCN)=O.[H]Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ketcham JM, et al. Design and Discovery of MRTX0902, a Potent, Selective, Brain-Penetrant, and Orally Bioavailable Inhibitor of the SOS1:KRAS Protein-Protein Interaction. J Med Chem. 2022 Jul 28;65(14):9678-9690.
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