Cart
sales@molnova.com
Afimetoran
CAS No. 2171019-55-7
Afimetoran( BMS-986256 )
Catalog No. M28229 CAS No. 2171019-55-7
Afimetoran is a toll-like receptor antagonist, which can be used in the research of inflammatory and autoimmune diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 215 | In Stock |
|
| 5MG | 187 | In Stock |
|
| 10MG | 312 | In Stock |
|
| 25MG | 530 | In Stock |
|
| 50MG | 733 | In Stock |
|
| 100MG | 1042 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAfimetoran
-
NoteResearch use only, not for human use.
-
Brief DescriptionAfimetoran is a toll-like receptor antagonist, which can be used in the research of inflammatory and autoimmune diseases.
-
DescriptionAfimetoran is a toll-like receptor antagonist, which can be used in the research of inflammatory and autoimmune diseases.
-
In Vitro——
-
In Vivo——
-
SynonymsBMS-986256
-
PathwayImmunology/Inflammation
-
TargetTLR
-
Recptormitotic kinesin Kif18A
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2171019-55-7
-
Formula Weight444.57
-
Molecular FormulaC26H32N6O
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (224.94 mM)
-
SMILESCC(C)c1c(-c2cn3ncnc3c(C)c2C)[nH]c2c1cc(C1CCN(CC(N)=O)CC1)cc2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Tamayo NA, et al. Targeting the Mitotic Kinesin KIF18A in Chromosomally Unstable Cancers: Hit Optimization Toward an In Vivo Chemical Probe. J Med Chem. 2022;65(6):4972-4990.
molnova catalog
related products
-
CEP-40783
CEP-40783 is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM).
-
Telratolimod
Telratolimod is a toll-like receptors 7/8 agonist. It has an antitumor activity.
-
Isatoribine
Isatoribine (ANA245;7-Thia-8-oxoguanosine;Immunosine) is a nucleoside analogue, selective agonist of TLR7 with significant antiviral effect and mmunoenhancing activity.
