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Lalistat 1

CAS No. 501104-16-1

Lalistat 1( ZINC795230 )

Catalog No. M28175 CAS No. 501104-16-1

Lalistat 1 is an inhibitor of lysosomal acid lipase (LAL, IC50 = 68 nM) and IgA1 protease for H. influenzae.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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10MG	60	In Stock
25MG	93	In Stock
50MG	138	In Stock
100MG	202	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
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Biological Information

Product Name

Lalistat 1
Note

Research use only, not for human use.
Brief Description

Lalistat 1 is an inhibitor of lysosomal acid lipase (LAL, IC50 = 68 nM) and IgA1 protease for H. influenzae.
Description

Lalistat 1 is an inhibitor of lysosomal acid lipase (LAL, IC50 = 68 nM) and IgA1 protease for H. influenzae. Lalistat 1 can be used in studies about niemann-pick type C diseases.(In Vitro):Lalistat 1 (0-100 μM) dose-dependently inhibits IgA1P B1 and B2, almost completely at 50 μM and completely at 100 μM .Lalistat 1 reduces cholesterol accumulation in lysosome-like reservoirs of GM03123 human fibroblasts lacking NPC1 .
In Vitro

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In Vivo

——
Synonyms

ZINC795230
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

MMP-12
Research Area

——
Indication

——

Chemical Information

CAS Number

501104-16-1
Formula Weight

298.36
Molecular Formula

C12H18N4O3S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 20 mg/mL (67.03 mM)
SMILES

O=C(Oc1nsnc1N1CCCCC1)N1CCOCC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Morales R, et al. Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12. J Mol Biol. 2004 Aug 20;341(4):1063-76.

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