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Lalistat 1
CAS No. 501104-16-1
Lalistat 1( ZINC795230 )
Catalog No. M28175 CAS No. 501104-16-1
Lalistat 1 is an inhibitor of lysosomal acid lipase (LAL, IC50 = 68 nM) and IgA1 protease for H. influenzae.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 44 | In Stock |
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| 10MG | 60 | In Stock |
|
| 25MG | 93 | In Stock |
|
| 50MG | 138 | In Stock |
|
| 100MG | 202 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLalistat 1
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NoteResearch use only, not for human use.
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Brief DescriptionLalistat 1 is an inhibitor of lysosomal acid lipase (LAL, IC50 = 68 nM) and IgA1 protease for H. influenzae.
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DescriptionLalistat 1 is an inhibitor of lysosomal acid lipase (LAL, IC50 = 68 nM) and IgA1 protease for H. influenzae. Lalistat 1 can be used in studies about niemann-pick type C diseases.(In Vitro):Lalistat 1 (0-100 μM) dose-dependently inhibits IgA1P B1 and B2, almost completely at 50 μM and completely at 100 μM .Lalistat 1 reduces cholesterol accumulation in lysosome-like reservoirs of GM03123 human fibroblasts lacking NPC1 .
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In Vitro——
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In Vivo——
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SynonymsZINC795230
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorMMP-12
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Research Area——
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Indication——
Chemical Information
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CAS Number501104-16-1
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Formula Weight298.36
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Molecular FormulaC12H18N4O3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 20 mg/mL (67.03 mM)
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SMILESO=C(Oc1nsnc1N1CCCCC1)N1CCOCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Morales R, et al. Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12. J Mol Biol. 2004 Aug 20;341(4):1063-76.
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