Propargylcholine

Research use only, not for human use.

Propargylcholine is an alkyne-modified choline analog and inhibits choline catabolism at the level of Dgc enzyme-catalyzed dimethylglycine demethylation in Pseudomonas aeruginosa.

Propargylcholine is an alkyne-modified choline analog and inhibits choline catabolism at the level of Dgc enzyme-catalyzed dimethylglycine demethylation in Pseudomonas aeruginosa.

Propargylcholine bromide (10, 50 μM; 24 h) incorporates into NIH 3T3 cells and shows strong staining in a concentration-dependent manner (fixed and stained with Alexa568-azide). Immunofluorescence Cell Line:NIH 3T3 cells Concentration:10, 50 μM Incubation Time:24 h Result:Showed strong staining proportional in intensity to the concentration of added Propargylcholine bromide.

Propargylcholine bromide (P-Cho; 3.5-4.0 mg/kg; i.p; single daily for 6 days) effectivelyincorporates into newly synthesized myelin within 1 week of dosing and sustained presence beyond 6 weeks in rhesus monkey.

Propargylcholine (bromide)

GPCR/G Protein

Antibacterial

Bacterial|PGE2|COX-1|E. coli

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111755-76-1

208.099

C7H14BrNO

>98% (HPLC)

In Vitro:?H2O : 125 mg/mL (600.67 mM)

[Br-].C[N+](C)(CCO)CC#C

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(-20℃)

With Ice Pack

≥ 2 years