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N-Acetyltyramine
CAS No. 1202-66-0
N-Acetyltyramine( —— )
Catalog No. M28125 CAS No. 1202-66-0
N-Acetyltyramine is the active compound extracted from a fermentation broth of strain M3-10 which produces quorum-sensing inhibitor (QSI) compound. N-Acetyltyramine inhibits Chromobacterium violaceum ATCC 12472 violacein production and virulence factors, such as pyoverdine production, as well as swarming and twitching motilities, produced by Pseudomonas aeruginosa PAO1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 32 | In Stock |
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| 5MG | 28 | In Stock |
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| 10MG | 46 | In Stock |
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| 25MG | 74 | In Stock |
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| 50MG | 110 | In Stock |
|
| 100MG | 164 | In Stock |
|
| 200MG | 245 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameN-Acetyltyramine
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NoteResearch use only, not for human use.
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Brief DescriptionN-Acetyltyramine is the active compound extracted from a fermentation broth of strain M3-10 which produces quorum-sensing inhibitor (QSI) compound. N-Acetyltyramine inhibits Chromobacterium violaceum ATCC 12472 violacein production and virulence factors, such as pyoverdine production, as well as swarming and twitching motilities, produced by Pseudomonas aeruginosa PAO1.
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DescriptionN-Acetyltyramine is the active compound extracted from a fermentation broth of strain M3-10 which produces quorum-sensing inhibitor (QSI) compound. N-Acetyltyramine inhibits Chromobacterium violaceum ATCC 12472 violacein production and virulence factors, such as pyoverdine production, as well as swarming and twitching motilities, produced by Pseudomonas aeruginosa PAO1.(In Vitro):N-Acetyltyramine enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells (IC50 = 0.13 μg/ml).
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In VitroN-Acetyltyramine enhances cytotoxicity of doxorubicin in resistant P388 murine leukemia cells with an IC50 value of 0.13 μg/ml compared with an IC50 value of 0.48 μg/ml for doxorubicin alone.
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorWee1
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Research Area——
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Indication——
Chemical Information
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CAS Number1202-66-0
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Formula Weight179.219
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Molecular FormulaC10H13NO2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (557.97 mM)
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SMILESCC(=O)NCCc1ccc(O)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Huang PQ, et al. Discovery of ZN-c3, a Highly Potent and Selective Wee1 Inhibitor Undergoing Evaluation in Clinical Trials for the Treatment of Cancer. J Med Chem. 2021 Sep 9;64(17):13004-13024.
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