Orellanine

CAS No. 37338-80-0

Orellanine( 2-(1,3-dihydroxy-4-oxopyridin-2-yl)-1,3-dihydroxypyridin-4-one )

Catalog No. M28005 CAS No. 37338-80-0

Orellanine is a nephrotoxic compound extracted from the mushroom Cortinarius orellanus.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 695 In Stock
5MG 753 In Stock
10MG 1102 In Stock
25MG 1758 In Stock
50MG 2399 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Orellanine
  • Note
    Research use only, not for human use.
  • Brief Description
    Orellanine is a nephrotoxic compound extracted from the mushroom Cortinarius orellanus.
  • Description
    Orellanine is a nephrotoxic compound extracted from the mushroom Cortinarius orellanus. Orellanine strongly inhibits the synthesis of macromolecules (Proteins, RNA and DNA) in Madin-Darby canine kidney cells and in rat liver mitochondria.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    2-(1,3-dihydroxy-4-oxopyridin-2-yl)-1,3-dihydroxypyridin-4-one
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    bradykinin B1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    37338-80-0
  • Formula Weight
    252.182
  • Molecular Formula
    C10H8N2O6
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Oc1cc[n+]([O-])c(c1O)-c1c(O)c(O)cc[n+]1[O-]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Leeb-Lundberg LM, et al. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar;57(1):27-77.
molnova catalog
related products
  • DO-264

    DO-264 is an inhibitor of autohydrolase structural domain 12 (ABHD12) (IC50: 11 nM) and an inhibitor of cellular LysoPS degradation that enhances LPS-induced phagocytosis.

  • Praliciguat

    Praliciguat stimulates sGC in HEK-293 cells (EC50: 197 nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator.

  • Broxiquinoline

    Broxyquinoline is an antiprotozoal agent and able to release oxygen free radicals from the water in mucous membranes.