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Cerlapirdine
CAS No. 925448-93-7
Cerlapirdine( SAM531 | SAM-531 | SAM 531 | PF-05212365 | P -05212365 | WAY-262,531 )
Catalog No. M27966 CAS No. 925448-93-7
Cerlapirdine is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine is already in clinical development for the treatment of cognitive disorders related to Alzheimer's disease and schizophrenia. It works by acting as a selective 5-HT6 receptor antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 160 | Get Quote |
|
| 10MG | 260 | Get Quote |
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| 25MG | 515 | Get Quote |
|
| 50MG | 740 | Get Quote |
|
| 100MG | 1017 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameCerlapirdine
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NoteResearch use only, not for human use.
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Brief DescriptionCerlapirdine is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine is already in clinical development for the treatment of cognitive disorders related to Alzheimer's disease and schizophrenia. It works by acting as a selective 5-HT6 receptor antagonist.
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DescriptionCerlapirdine is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine is already in clinical development for the treatment of cognitive disorders related to Alzheimer's disease and schizophrenia. It works by acting as a selective 5-HT6 receptor antagonist.
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In Vitro——
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In Vivo——
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SynonymsSAM531 | SAM-531 | SAM 531 | PF-05212365 | P -05212365 | WAY-262,531
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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RecptorhSmo|mSmo
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Research Area——
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Indication——
Chemical Information
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CAS Number925448-93-7
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Formula Weight409.5
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Molecular FormulaC22H23N3O3S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 41.67 mg/mL (101.76 mM)
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SMILESCN(C)CCCOc1ccc2n[nH]c(c2c1)S(=O)(=O)c1cccc2ccccc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Lauressergues E, et al. Pharmacological evaluation of a series of smoothened antagonists in signaling pathways and after topical application in a depilated mouse model. Pharmacol Res Perspect. 2016 Mar 4;4(2):e00214.
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