Cart
sales@molnova.com
Cerlapirdine
CAS No. 925448-93-7
Cerlapirdine( SAM531 | SAM-531 | SAM 531 | PF-05212365 | P -05212365 | WAY-262,531 )
Catalog No. M27966 CAS No. 925448-93-7
Cerlapirdine is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine is already in clinical development for the treatment of cognitive disorders related to Alzheimer's disease and schizophrenia. It works by acting as a selective 5-HT6 receptor antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 199 | In Stock |
|
| 5MG | 169 | In Stock |
|
| 10MG | 275 | In Stock |
|
| 25MG | 543 | In Stock |
|
| 50MG | 764 | In Stock |
|
| 100MG | 1051 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCerlapirdine
-
NoteResearch use only, not for human use.
-
Brief DescriptionCerlapirdine is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine is already in clinical development for the treatment of cognitive disorders related to Alzheimer's disease and schizophrenia. It works by acting as a selective 5-HT6 receptor antagonist.
-
DescriptionCerlapirdine is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine is already in clinical development for the treatment of cognitive disorders related to Alzheimer's disease and schizophrenia. It works by acting as a selective 5-HT6 receptor antagonist.
-
In Vitro——
-
In Vivo——
-
SynonymsSAM531 | SAM-531 | SAM 531 | PF-05212365 | P -05212365 | WAY-262,531
-
PathwayEndocrinology/Hormones
-
Target5-HT Receptor
-
RecptorhSmo|mSmo
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number925448-93-7
-
Formula Weight409.5
-
Molecular FormulaC22H23N3O3S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 41.67 mg/mL (101.76 mM)
-
SMILESCN(C)CCCOc1ccc2n[nH]c(c2c1)S(=O)(=O)c1cccc2ccccc12
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Lauressergues E, et al. Pharmacological evaluation of a series of smoothened antagonists in signaling pathways and after topical application in a depilated mouse model. Pharmacol Res Perspect. 2016 Mar 4;4(2):e00214.
molnova catalog
related products
-
JNJ-5234801
JNJ-5234801 is an atypical anxiolytic targeting 5-HT2 receptor, has demonstrated oral activity in animal models of anxiety.
-
CART (62-76) (rat, h...
Cocaine- and amphetamine-regulated transcript (CART) peptide fragment that inhibits food intake. Attenuates NPY-induced feeding and decreases food intake in food-restricted goldfish, and induces anxiogenic-like effects in elevated plus-maze test in rats. Modulates the activity of striatal noradrenergic, and corticostrial and hypothalamic serotoninergic systems, with no major effect on dopaminergic pathways in rat brain.
-
Minaprine
Minaprine is a psychotropic drug which has proved to be effective in the treatment of various depressive states.
