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Sergliflozin etabonate
CAS No. 408504-26-7
Sergliflozin etabonate( GW-869682 | GW-869682X | KGT-1251 | GW869682 | GW869682X | KGT1251 | )
Catalog No. M27926 CAS No. 408504-26-7
Sergliflozin etabonate, a SGLT-2 inhibitor, is used potentially for the treatment of type 2 diabetes and obesity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 212 | In Stock |
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| 5MG | 215 | In Stock |
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| 10MG | 321 | In Stock |
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| 25MG | 519 | In Stock |
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| 50MG | 677 | In Stock |
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| 100MG | 923 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSergliflozin etabonate
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NoteResearch use only, not for human use.
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Brief DescriptionSergliflozin etabonate, a SGLT-2 inhibitor, is used potentially for the treatment of type 2 diabetes and obesity.
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DescriptionSergliflozin etabonate, a SGLT-2 inhibitor, is used potentially for the treatment of type 2 diabetes and obesity.
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In Vitro——
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In VivoAnimal Model:14 weeks, Female KK-Ay mice Dosage:1, 3, 10, 30 mg/kg Administration:Oral; once Result:Significantly reduced non-fasting blood glucose level with the reduction in blood glucose level at 2 h post dosing in the 1 mg/kg group, 3 mg/kg group, 10 mg/kg group, and 30 mg/kg group was 12, 15, 28, and 39%, respectively.Animal Model:4 weeks, Female KK-Ay mice Dosage:1.7, 8.4, 45.7 mg/kg in the 0.001, 0.005, and 0.025% sergliflozin etabonate Administration:Fed, daily for 9 weeks Result:Reduced non-fasting blood glucose level and decreased triglyceride content in the liver in a dose-dependent manner in diabetic control KK-Ay mice.
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SynonymsGW-869682 | GW-869682X | KGT-1251 | GW869682 | GW869682X | KGT1251 |
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PathwayOthers
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TargetOther Targets
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Recptorprotoporphyrinogen oxidase
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Research Area——
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Indication——
Chemical Information
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CAS Number408504-26-7
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Formula Weight448.468
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Molecular FormulaC23H28O9
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Purity>98% (HPLC)
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Solubility——
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SMILESCCOC(=O)OC[C@H]1O[C@@H](Oc2ccccc2Cc2ccc(OC)cc2)[C@H](O)[C@@H](O)[C@@H]1O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Asher, Brady Scott, et al. Vertical mobility, soil adsorption, and cotton tolerance to three Protoporphyrinogen oxidase (PPO) inhibiting herbicides in three West Texas soils. Texas tech university.
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