PD 174265

CAS No. 216163-53-0

PD 174265( PD174265 | PD-174265 | N-{4-[(3-Bromophenyl)amino]quinazolin-6-Yl}propanamide )

Catalog No. M27910 CAS No. 216163-53-0

PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 36 In Stock
5MG 29 In Stock
10MG 36 In Stock
25MG 54 In Stock
50MG 74 In Stock
100MG 108 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    PD 174265
  • Note
    Research use only, not for human use.
  • Brief Description
    PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.
  • Description
    PD 174265 is an effective, selective and reversible inhibitor of epidermal growth factor receptor (EGFR) with an IC50 of 0.45 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    PD174265 | PD-174265 | N-{4-[(3-Bromophenyl)amino]quinazolin-6-Yl}propanamide
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    Influenza Virus
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    216163-53-0
  • Formula Weight
    371.238
  • Molecular Formula
    C17H15BrN4O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (336.72 mM)
  • SMILES
    CCC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Takizawa N, et al. Anti-influenza virus activity of a salcomine derivative mediated by inhibition of viral RNA synthesis. Arch Virol. 2018 Jun;163(6):1607-1614.
molnova catalog
related products
  • Tyrphostin A1

    Tyrphostin A1 is an inhibitor of EGFR tyrosine kinase .

  • BI-4020

    BI-4020 is a fourth-generation, non-covalent, and orally active inhibitor of EGFR tyrosine kinase.

  • (Rac)-JBJ-04-125-02

    JBJ-04-125-02 is effective as a single agent in both in vitro and in vivo models of EGFR-mutant lung cancer.