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Dexelvucitabine

CAS No. 134379-77-4

Dexelvucitabine( beta-D-D-4FC | D-D-4FC | DFC | DPC-817 | RVT )

Catalog No. M27870 CAS No. 134379-77-4

Dexelvucitabine, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Dexelvucitabine
  • Note
    Research use only, not for human use.
  • Brief Description
    Dexelvucitabine, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.
  • Description
    Dexelvucitabine, a nucleoside reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.
  • In Vitro
    ——
  • In Vivo
    Dexelvucitabine (Reverset; d-d4FC; 33.3 mg/kg by i.v. or p.o.) has distribution and elimination half-lives (t1/2α?and?t1/2β, respectively) of 0.7 and 3.6 hin monkeys, respectively. The Cmax ranges from 21.1 to 47.5 μM. Dexelvucitabine has a favorable pharmacokinetic profile with a long half-life (4.71 and 10.75 h after administration by the intravenous [i.v.] and oral [p.o.] routes, respectively)?in woodchucks.
  • Synonyms
    beta-D-D-4FC | D-D-4FC | DFC | DPC-817 | RVT
  • Pathway
    Microbiology/Virology
  • Target
    Reverse Transcriptase
  • Recptor
    inflammation
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    134379-77-4
  • Formula Weight
    227.195
  • Molecular Formula
    C9H10FN3O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (220.08 mM)
  • SMILES
    Nc1nc(=O)n(cc1F)[C@@H]1O[C@H](CO)C=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Park, Seul-Ki, Lee, Mi-Young. Inhibitory effects of chiisanoside and acanthoside on the allergic inflammation.Molecular and Cellular Toxicology, 2007, 3(4):60-60.
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