Cart
sales@molnova.com
AVN-101 hydrochloride?
CAS No. 1061354-48-0
AVN-101 hydrochloride?( AVN 101 | AVN101 )
Catalog No. M27852 CAS No. 1061354-48-0
AVN-101 is a very potent 5-HT7 receptor antagonist (Ki = 153 pM). AVN-101 also exhibits a rather high affinity toward histamine H1 (Ki = 0.58 nM) and adrenergic α2A, α2B, and α2C (Ki = 0.41-3.6 nM) receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 302 | Get Quote |
|
| 10MG | 447 | Get Quote |
|
| 25MG | 714 | Get Quote |
|
| 50MG | 1017 | Get Quote |
|
| 100MG | 1368 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameAVN-101 hydrochloride?
-
NoteResearch use only, not for human use.
-
Brief DescriptionAVN-101 is a very potent 5-HT7 receptor antagonist (Ki = 153 pM). AVN-101 also exhibits a rather high affinity toward histamine H1 (Ki = 0.58 nM) and adrenergic α2A, α2B, and α2C (Ki = 0.41-3.6 nM) receptors.
-
DescriptionAVN-101 is a very potent 5-HT7 receptor antagonist (Ki = 153 pM). AVN-101 also exhibits a rather high affinity toward histamine H1 (Ki = 0.58 nM) and adrenergic α2A, α2B, and α2C (Ki = 0.41-3.6 nM) receptors. AVN-101 shows a good oral bioavailability and facilitated brain-blood barrier permeability, low toxicity, and reasonable efficacy in animal models of CNS diseases.
-
In Vitro——
-
In Vivo——
-
SynonymsAVN 101 | AVN101
-
PathwayEndocrinology/Hormones
-
Target5-HT Receptor
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1061354-48-0
-
Formula Weight340.9
-
Molecular FormulaC21H25ClN2
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCl.CN1CCc2c(C1)c1cc(C)ccc1n2CCc1ccccc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Nathaniel J Henning, et al. Deubiquitinase-targeting chimeras for targeted protein stabilization. Nat Chem Biol. 2022;18(4):412-421.
molnova catalog
related products
-
Blonanserin
Blonanserin is a novel atypical antipsychotic agent with potent dopamine D2 and serotonin 5-HT2 receptors antagonist properties.
-
Alisol A 24-acetate
Alisol A 24-acetate has been determined for the quality control of this crude drug.
-
Espindolol
Espindolol is a novel non-selective β blocker with central 5-HT1a and partial β2 receptor agonist effects.
