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Home - Products - Metabolic Enzyme/Protease - DPP - Diprotin A

Diprotin A

CAS No. 90614-48-5

Diprotin A( Ile-Pro-Ile )

Catalog No. M27813 CAS No. 90614-48-5

Diprotin A (Ile-Pro-Ile) is an inhibitor of dipeptidyl peptidase IV (DPP-IV).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 33 In Stock
10MG 32 In Stock
25MG 55 In Stock
50MG 87 In Stock
100MG 132 In Stock
200MG 184 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Diprotin A
  • Note
    Research use only, not for human use.
  • Brief Description
    Diprotin A (Ile-Pro-Ile) is an inhibitor of dipeptidyl peptidase IV (DPP-IV).
  • Description
    Diprotin A (Ile-Pro-Ile) is an inhibitor of dipeptidyl peptidase IV (DPP-IV).
  • In Vitro
    Western Blot Analysis Cell Line:Human endothelial cells Concentration:100?μM Incubation Time:30?minutes after CXCR4-blocker or Src-inhibitor treatment Result:Induced the phosphorylation of Src [Tyr 416] and VE-cadherin [Tyr731] in hECs.
  • In Vivo
    Animal Model:Streptozotocin-induced diabetic retinopathy model in wild-type C57/BL6 mice Dosage:70?μg/kg Administration:Intraperitoneal injection; twice daily; 7 days Result:Induced vascular leakage by augmenting the SDF-1α/CXCR4/Src/VE-cadherin signaling pathway.
  • Synonyms
    Ile-Pro-Ile
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    DPP
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    90614-48-5
  • Formula Weight
    341.452
  • Molecular Formula
    C17H31N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?H2O : ≥ 100 mg/mL (292.87 mM))
  • SMILES
    CC[C@H](C)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Itkin M, et al. The biosynthetic pathway of the nonsugar, high-intensity sweetener mogroside V from Siraitia grosvenorii.Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7619-E7628.
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