TCS 46b

CAS No. 302799-86-6

TCS 46b( —— )

Catalog No. M27726 CAS No. 302799-86-6

TCS 46b is a NR1A/NR2B NMDA receptor antagonist with oral activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 37 In Stock
5MG 62 In Stock
10MG 101 In Stock
25MG 212 In Stock
50MG 333 In Stock
100MG 551 In Stock
200MG 728 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    TCS 46b
  • Note
    Research use only, not for human use.
  • Brief Description
    TCS 46b is a NR1A/NR2B NMDA receptor antagonist with oral activity.
  • Description
    TCS 46b is a NR1A/NR2B NMDA receptor antagonist with oral activity.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Sprague?Dawley rats, 6-hydroxydopamine-lesioned (6-OHDA) rat modelDosage:10 and 30 mg/kg Administration:PO or IP, once Result:Showed significant potentiation of the effects of L-DOPA in this model.
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    NMDAR
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    302799-86-6
  • Formula Weight
    345.446
  • Molecular Formula
    C22H23N3O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (289.49 mM)
  • SMILES
    O=c1[nH]c2ccc(cc2[nH]1)C#CCN1CCC(Cc2ccccc2)CC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Fdez Galván I, et al. Solvent Effects on the Structure and Spectroscopy of the Emitting States of 1-Phenylpyrrole. J Chem Theory Comput. 2011 Jun 14;7(6):1850-7.
molnova catalog
related products
  • Picroside III

    Picroside III, an iridoid glucoside found in the root of Picrorhiza scrophulariiflora Pennell (Scrophulariaceae), and its subtype Picroside II has been demonstrated to reduce apoptosis in neuronal cells and other cell types.

  • Ro 8-4304 Hydrochlor...

    Ro 8-4304 Hydrochloride is an antagonist of NMDA receptor with IC50 of 0.4 μM?Ro 8-4304 is a voltage-independent, non-competitive antagonist of NMDA receptors in rat cultured cortical neurones and exhibits a state-dependent mode of action similar to that described for ifenprodil.

  • Glypromate

    Glypromate is a neuroprotective agent is a weak NMDA receptor agonist.