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Sonepiprazole

CAS No. 170858-33-0

Sonepiprazole( PNU-101387G | U-101387G )

Catalog No. M27715 CAS No. 170858-33-0

Sonepiprazole (PNU-101387G) is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 129 Get Quote
25MG 285 Get Quote
50MG 484 Get Quote
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Biological Information

  • Product Name
    Sonepiprazole
  • Note
    Research use only, not for human use.
  • Brief Description
    Sonepiprazole (PNU-101387G) is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively.
  • Description
    Sonepiprazole (PNU-101387G) is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively.
  • In Vitro
    Sonepiprazole exhibits highly specific binding to the D4 dopamine receptor with more than 100-fold selectivity for the D4 receptor over other receptors, including dopamine, serotonin, and adrenergic receptors.
  • In Vivo
    ——
  • Synonyms
    PNU-101387G | U-101387G
  • Pathway
    GPCR/G Protein
  • Target
    Dopamine Receptor
  • Recptor
    NOX1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    170858-33-0
  • Formula Weight
    401.53
  • Molecular Formula
    C21H27N3O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (311.32 mM)
  • SMILES
    NS(=O)(=O)c1ccc(cc1)N1CCN(CC[C@H]2OCCc3ccccc23)CC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Brown SJ, et al. Probe Report for NOX1 Inhibitors. 2009 Apr 23 [updated 2010 Sep 2]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–.
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